Sentence examples for multiple regulatory inputs from inspiring English sources

NHRs control the transcription of remarkably diverse and specific gene networks, apparently by integrating multiple regulatory inputs that interact with distinct receptor surfaces; these inputs include small molecule ligands, transcriptional coregulators, and response elements, the genomic sites to which the receptors bind.

Specifically, we use the bacterial σ70 promoter of E. coli as a simple experimental model system to explore the ability of individual promoters to integrate multiple regulatory inputs, with the goal of uncovering simple rules or cis regulatory codes that may connect certain promoter architectures to their function.

Integrating multiple regulatory inputs on RNA molecules can also be subject to undesigned interaction that could undermine functionality.

Thus, TGFβ signalling orchestrates StC flattening via multiple regulatory inputs of adhesion molecules and of the components of the actin cytoskeleton.

Although at the cellular level many developmental decisions can be broken down to a simple choice between two outcomes, it is clear that there are multiple regulatory inputs into that decision (reviewed by [ 1]).

The acquisition of specific microglial phenotypes is a consequence of multiple regulatory inputs provided by interactions with neurons, glia and CNS-infiltrating immune cells (Carson et al., 2007; Tian et al., 2009).

We discuss the molecular mechanisms that enable and accompany the action of long-range acting elements and the integration of multiple distributed regulatory inputs into the coherent and specific regulatory programs that are key to embryonic development.

The production of NICD within a given cell is therefore a multicellular process with multiple oscillatory regulatory inputs.

Alternatively, or possibly concurrently, persistence of Salmonella inside tomatoes is a complex phenotype, controlled by multiple nutritional and regulatory inputs that are redundant, making the expression of individual genes less important.

In particular, because in our model the promoter's expression is a linear function of the regulatory inputs, the theory extends easily to promoters coupling to multiple regulators with different coupling constants.

Barclays has had to pay multiple fines in multiple jurisdictions over the last few years for multiple regulatory failures.