Sentence examples for multiple regulatory events from inspiring English sources

The action of heparanase is involved in multiple regulatory events related, among other effects, to augmented bioavailability of growth factors and cytokines.

HDAC6 has been involved in multiple regulatory events related to development or disease, interacting with different proteins.

The decreased expression of miR-124 in carcinomas may result from multiple regulatory events, including the methylation of CpG islands.

Multiple regulatory events, termed checkpoints, verify whether certain cellular processes have occurred properly before allowing the cells to proceed from one phase to another [ 2– 6].

We conclude that inefficient pre-mRNA splicing may interfere with multiple posttranscriptional regulatory events, which has to be considered when interpreting results of genetic interaction screens.

This perspective is in line with the 'thermodynamic' models of gene regulation that combine multiple transcriptional regulatory events such as TF binding into a single probabilistic framework 51, 52.

The results showed a clear effect of golli on OPC development and support a role for golli in modulating multiple Ca2+-regulatory events through VOCCs and SOCCs.

Furthermore, blood-feeding triggers a cascade of gene regulatory events in multiple tissues including midgut through the interplay of endocrine signals and transcription factors and thus has great impact on mosquito biology [ 33- 36].

The UA9 motif logo (supplementary fig. S5 B and C, Supplementary Material online) was previously associated with TF-binding events of multiple regulatory proteins exclusively in H1-hESCs, including NANOG, BCL11A, HDAC2, ESR1, GATA2, RXRA, TCF12, and a subset of HDAC2-associated POU5F1-binding sites (Wang et al. 2012).

A loss of 14-3-3 14-3-3 14-3-3sturbs thexpression regulatory pathways andisturbsearly eventhen neoplastic transformultiplecaregulatoryis, and subsequently increasing radiosensitivity (Nakajima et al. 2003; Mhawech, 2005).

These and other properties are ideal for proteins that mediate signaling, transcription and coordinate regulatory events, where binding to multiple partners in high-specificity/low-affinity interactions are paramount [ 5].