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Just as in the past, executives realize they need to fight the battle on multiple regulatory and legal fronts.
The scrutiny of Mr. Winnick, who was the nonexecutive chairman of Global Crossing, by multiple regulatory and legislative bodies during investigations into the company was extensive and unprecedented; he cooperated willingly, answered every question and, in the end, was completely vindicated.
The most common route of lead exposure is through ingestion, and multiple regulatory and guidance values exist to limit lead ingestion in the U.S. (ATSDR 2007a).
Each of these transitions rely on signal cascades with multiple regulatory and feedback loops allowing both plasticity and cooperation during development.
Chemical and biological sensing are problems of tremendous contemporary technological importance in multiple regulatory and human health contexts, including environmental monitoring, water quality assurance, workplace air quality assessment, food quality control, many aspects of biodiagnostics, and, of course, homeland security.
As with human DNA-dependent DNA polymerases, RNA polymerase II, the enzyme that transcribes most of the genes in the human genome, operates as part of a large protein complex with multiple regulatory and accessory subunits.
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Other groups have investigated the non-coding regulatory elements within disease genes such as RET (Ret proto-oncogene) and MECP2 (Methyl-CpG binding protein 2) and found multiple regulatory enhancer and silencer elements.
Myosin VI's involvement in these cellular pathways is mediated by its interaction with specific adaptor proteins and is regulated by multiple regulatory signals and modifications such as calcium ions, PtdIns(4,5 P2 (PIP2) and phosphorylation.
The situation was even more complicated for businesses that operate internationally and need to deal with multiple regulatory regimes and payment endpoints.
Multiple regulatory agencies and public health organizations use the term, and in some cases define the term.
Placement enrichment of primate- and human-specific TF-binding sites at selected genomic regions may facilitate chromatin remodeling and transition to the permissive chromatin states (Ernst and Kellis 2013), enabling binding of multiple regulatory proteins and cobinding of many TFs at specific loci (supplementary figs. S9 S11, Supplementary Material online).
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