The Delay-type operons are commonly involved in carbon metabolism and are regulated by multiple regulators and are regulated via multiple promoters, whereas, the Basic-type operons are more diverse, both in the functions they perform, as well as, in the number of regulators that control them.
We examined the regulation of ORB+ genes to determine if they are any more or less likely than genes which have been transferred intact to be regulated by multiple regulators, and found no difference in the relative complexity of regulation of ORB+ and ORB- lateral gene sets (P = 0.96, by the Wilcoxon rank sum test).
to apply to regulation processes involving multiple regulators and transcription complexes composed of several genes, we allow a transition t to have an arbitray number of inputs I t ={ it,…, it k } and outputs O t ={ ot,…, ot l }.
Because of their indispensable role in pathogenicity, expression of CWDE is strictly regulated at the transcriptional level by multiple regulators and further fine tuned by environmental factors including pH, osmolarity and O2 concentrations all of which influence the successful onset of disease symptoms [ 70].
In this study, we use multi-input/single-output regulatory model to dynamically describe our gene regulatory system (i.e. multiple regulators and one target gene) that can mimic the real gene regulation in response to inflammation.
Over time, we have developed a complex web of bureaucratic hurdles, multiple regulators and policy ambivalence on significant issues.
"There are multiple regulators witnessing and conducting these tests to be absolutely sure that the leak is sealed," she said.
Intriguingly, genes involved in metabolic processes such as many nuclear hormone receptors (NHRs) and multiple regulators of sterol and fatty-acid metabolism constitute candidate targets of PHA-4 in starved larvae.
Many identified transcription factors are unknown but include functional domains present in multiple regulators of development and interestingly, ratios between regulators with domains changed by stages.
For example, when cells experience ultraviolet (UV) irradiation and DNA damage, CRL4A becomes activated and targets multiple regulators of the cell cycle and DNA replication pathways as well as DNA repair proteins.
"There should be order within Europe and a single regulator that regulates you, not multiple regulators all trying to regulate everything in their own different ways," he said.
