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This underexpression could be in part the result of chromosome 4q deletion but also the consequence of multiple regulation loops that are deregulated in cancer cells.
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Some of the factors can be transcriptionally regulated by p63, forming some regulation loops.
We focus on repression-based transcriptional regulation loops composed of three genes, i.e. repressilators.
The controller was composed by two main loops, namely, current tracking loop and voltage regulation loop.
The design of the voltage regulation loop involves subsystem (13).
Therefore the controller can be splitted in two main loops, namely, current tracking loop and voltage regulation loop.
This autopilot is therefore based on an optic flow regulation loop.
These commonalities are important in complying with multiple regulations and for understanding regulations in general.
This provides the possibility to separate the design of the controller in two main loops, namely, current tracking loop and voltage regulation loop [29].
The proposed control law consists of two loops, which are referred as inner tracking loop and the outer voltage regulation loop.
In most cases, service sectors support multiple regulations to comply with government and industry regulations.
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