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This can help address scientific and policy questions, facilitate research, compare and pool results between registries, and use the strengths contained in multiple registries to generate new insights into treatments for ESRD patients.
A review of trial registries – ideally multiple registries to ensure a comprehensive and international approach – could be helpful to provide a more current overview of LMC involvement in oncology trials.
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This allowed us to triangulate multiple patient registries to maximize the number of retrievable patient records.
When registration in multiple registries is required (eg, to meet local regulation), each identifier should be clearly listed in the protocol and each registry.
We describe the potential for data linkage across multiple registries, which allows for access to medical histories with follow-up time spanning birth to death.
Most multiple sclerosis specialists in Sweden use the Swedish Multiple Sclerosis Registry to enter information on age at onset and sex as well as clinical parameters, such as disease course, bouts and treatment.
The validation study of the National Inpatient Register by Ludvigsson et al. (2011) found the overlap between the National Inpatient Register and Swedish Multiple Sclerosis Registry to be 52.9%, and 76.4% of all the cases in Swedish Multiple Sclerosis Registry were in the National Inpatient Register (Ludvigsson et al., 2011).
25 The strengths of our study are: (1) its population-based design; (2) the large sample size of over 20,000 PC patients; (3) the comprehensiveness of the Danish medical registries together with the ability to link data across multiple registries; and (4) the nature of the uniform health care system in Denmark that ensures equal access to free health care to all residents.
Weighted averages (using the total number of cases per registry to derive weights) were calculated to derive country-specific estimates where data on multiple registries per country were available.
Although there are obvious limitations of analyses within single sources, the combination of multiple registries also can be problematic as in addition to demographic and environmental differences between populations, case ascertainment and diagnostic criteria may also differ between sources (Loane et al., 2011).
Since then, multiple registries for many types of diseases have been used to assist the clinical research process [ 9- 13].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com