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It is not surprising, therefore, that there are multiple receptors for these substances.
The densities of multiple receptors for classical neurotransmitters also vary across the depth of the cortical ribbon, and thus determine the neurochemical properties of cyto- and myeloarchitectonic layers.
"The nose has multiple receptors for smell," said Dr. Allis Cho, an otolaryngologist on the medical staff at Texas Health Arlington Memorial Hospital.
Flaviviruses can utilize multiple receptors for different cell types and host species.
Prostaglandin E2 acts through multiple receptors, for example, EP1, EP2, EP3, EP4, and IP, and its effects are more variable.
Viruses that rely on multiple receptors for entry would be susceptible to this effect (e.g., HCV and HIV-1).
Similar(52)
The extracellular effects of HMGB1 are mediated via multiple receptors including the receptor for advanced glycated end-products (RAGE), some members of the TLR family and other as yet unidentified pathways [ 17, 24- 26].
Many GPCR ligands and substructures interact with multiple receptors, providing a basis for polypharmacological ligand design.
The latter sites appear to be more easily accessible, at least for multiple receptors.
Steroids also can act concurrently as agonists and antagonists for multiple receptors.
The ability of MG and BG to induce β-arrestin2-GFP translocation for multiple receptors in the presence of inhibitors, however, indicates that BG and MG do not behave as orthosteric receptor agonists.
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