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We realize, of course, that mirtazapine affects multiple receptor systems, including alpha-adrenergic, histamine type 1, and serotonin type 2 [5, 27, 28] receptors.
Conjugated gold nanoparticles that exhibit strong color change and localized surface plasmon resonance (LSPR) could be excellent candidates for potential multiple receptor systems such as aptamers, peptides, and antibodies [35, 43 45].
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We investigated the activity of multiple transmembrane receptor systems that possess neuromodulatory or neurotrophic actions.
Multisensory dizziness can be defined as dizziness attributed to increasing age and deterioration of multiple sensory receptor systems [ 5, 7].
The existence of multiple serotonergic receptor systems and dynamic compensation mechanisms creates difficulties for lesion and pharmacological studies (Barnes & Sharp, 1999).
Multisensory dizziness emerges due to the deterioration of multiple sensory receptor systems that occurs at old age and is established when all other vestibular disorders are excluded [ 4, 10].
Spontaneously active neuronal networks reflect the interactions of multiple neurotransmitter and receptor systems, and can reveal unexpected side effects due to secondary binding.
Thus, the effects of tamoxifen are complex and may be manifested through multiple and inter-related receptor systems.
Nonetheless, we identified significantly enriched pathways (i.e. hypergeometric p value, corrected for multiple hypothesis testing, <0.05) among the various combinations of receptor systems.
Early publications on receptor cooperativity were centered on receptor systems such as the cardiac muscarinic receptors [125].
The second type is referred to docking with multiple receptor structures, using pre-generated receptor conformers (Knegtel et al. 1997).
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