The Ad capsid structure is particularly well designed to mediate multiple receptor events.
Herein we report multiple receptor conformers based molecular docking as a practical alternative to account for the receptor flexibility.
We realize, of course, that mirtazapine affects multiple receptor systems, including alpha-adrenergic, histamine type 1, and serotonin type 2 [5, 27, 28] receptors.
Receptor structures were prepared for noncovalent docking as described.
*Sorafenib and Sunitinib target multiple receptor tyrosine kinases (RTKs) in addition to the aforementioned receptors.
We therefore searched specifically for domains forming receptor structures or involved in receptor functions.
The cell membrane is covered with flask-shaped membrane invaginations, sometimes shaped like a pocket and sometimes protruding out of the membrane, other times flattened, undistinguished from the basic structure of the cell membrane, but all of them very rich in lipids, sphingomyelin, complex protein structures and multiple receptors.
Privileged structures bind to multiple receptors with high affinity, thus aiding the development of novel biologically active compounds.
The remaining 407 structures (D1, 74; D2, 162; Dauto, 194) were evaluated, of which some affected multiple receptors.
Each receptor can bind multiple chemokines within its class and each chemokine can bind multiple receptors.
