We have revealed that adipocytes express cytokines, chemokines, multiple receptors, cell adhesion molecules and MHC class II family involved in (co)stimulation of T cell activation.
These results suggest that C-DIMs induce cell death in ER-negative breast cancer cells and this may be partially due to activation of autophagy and this demonstrates the versatility of this novel class of anticancer drugs which activate multiple receptor-independent cell death pathways in different cancer cell lines.
At the base of some of their eyes, there are multiple layers of receptor cells, including cells that are perpendicular to the axis of incoming light (distal retina), as well as a narrow second retina (proximal retina).
The class IA PI3-K signaling cascade is a crucial modulator linking the activation of multiple receptor classes to many core cell processes, including cell cycle, cell survival, protein synthesis, growth, metabolism, motility, and angiogenesis, via key signaling intermediates, including the SGK and AKT families.
It has been reported that cancer cells typically express multiple receptor tyrosine kinases (RTKs) that mediate the upregulation of cell-survival effectors, generally, phosphatidylinositol-3-OH kinase (PI3K) and mitogen-activated protein kinase (MAPK) [ 4].
It has been demonstrated that the plant response to ABA requires some key signaling components, including protein kinases, protein phosphatases and transcription factors, and it has also been generally recognized that the ABA signal is perceived by multiple receptors, at the cell surface or inside the cells (recently reviewed in [2] [5]).
Flaviviruses can utilize multiple receptors for different cell types and host species.
Thus, it appears that LRIG1 may control cell growth through antagonising multiple receptor tyrosine kinases.
Results from the RT-PCR analysis of the GABA receptors and transporters revealed that multiple isoforms are expressed in mouse circumvallate taste receptor cells.
Taste receptor cells (TRCs) in the circumvallate papillae express multiple subunits of the GABAA and GABAB receptors as well as multiple GATs.
