The Illinois Basin is a cratonic basin that formed as result of a failed early Cambrian rift that experienced multiple reactivations later in the Paleozoic (Leighton et al. 1990).
Thus, multiple HSV reactivations would lead to a progressive injury in parts of the brain that may favour the clinical expression of AD.
In combination with the interpretation of a UAV-based high-resolution digital surface model, multiple phases of reactivation are inferred.
In this syndrome, it was demonstrated by PCR analysis that there occurs a multiple and sequential reactivation of Herpes viruses in DIHS.
As for the pathogenesis of recrudescence of congenital infection, there are multiple possibilities: viral reactivation, lack of initial response due to interruption of therapy, ganciclovir-resistant virus, among others.
A molecular signature of cardiac hypertrophy is the reactivation of multiple genes that are active during fetal development but repressed in the adult heart [50].
This simultaneous reactivation of multiple targets provides a significant challenge to the understanding of the collective, and perhaps cooperative, effects of this phenomenon in cell transformation.
Combinations of targeted agents represent a potentially effective approach to simultaneously inhibiting multiple pathways, suppressing feedback reactivation of compensatory signaling network, and therefore to prevent recurrence.
Multiple mechanisms involving the reactivation of the mitogen-activated protein kinase (MAPK) pathway have been reported in vemurafenib-resistant BRAF V600E) mutant cancer cells.
