Sentence examples for multiple rarer variants from inspiring English sources

Rare variants were simulated as a single variant representing multiple rarer variants.

But the jury is still out on the catalog of rarer variants being developed by the 1,000 Genomes Project and how useful it will be, Dr. Goldstein said.

Back at the drawing board, biologists decided that if the genetic roots of common disease did not lie in the common variants, they should lie in the rarer variants.

However, the possible role of rarer variants or variants with a smaller effect size cannot at present be predicted.

We demonstrate that power of rare-variant association tests is higher in the Finnish population, especially when variants' phenotypic effects are tightly coupled with fitness effects and therefore reflect a greater contribution of rarer variants.

But researchers hope to find rarer variants and explore why, for example, some people who carry the well-known APOE4 risk gene never develop the disease.

The results indicate that the gradient is steeper for those with rarer variants.38 However, Conley and Rauscher (2013) advise caution when interpreting evidence from studies estimating G*E effects exploiting within-family variation.

These two variants are responsible for just a small fraction less than 1%—of the variation in caffeine intake among the subjects, suggesting that rarer variants, which this study didn't search for, are still out there, Cornelis says.

The data suggest an effect of rarer variants, possibly different among the three populations.

The tropism of certain parasite variants for multigravid women suggest that some rarer variants, probably not the most virulent can escape existing immunity to common VAR2CSA variants.

The merit of their method relies heavily on the assumption that rarer variants have larger per-allele effects.