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Multiple randomized trials, analyzed last October in the journal Obesity Reviews, have found a clear link between a child's preference for unhealthy foods and exposure to unhealthy food marketing.
Formulae to do this are uncommon because they require primary data from multiple randomized trials that measure both the surrogate and clinical outcome.
Hlatky said the idea for pooling raw individual patient data rather than simply using published results from multiple randomized trials of surgery and angioplasty was first proposed in 1995 by Stuart Pocock, PhD of the London School of Hygiene and Tropical Medicine, the senior author of the study.
It is presently under investigation in multiple randomized trials.
Multiple randomized trials have been conducted with Sr and Sm in patients with mCRPC.
In multiple randomized trials comparing BCT with mastectomy, their equality in overall survival has been shown [ 1- 7].
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In general, if the evidence base consists of multiple randomized controlled trials (RCTs) with each trial having at least one intervention in common with another, this network of RCTs can be synthesized with meta-analysis techniques: a network meta-analysis (or mixed treatment comparison meta-analysis) [ 1- 6].
Level of evidence: A, data derived from multiple randomized clinical trials or meta-analysis; B, data derived from a single randomized trial or non-randomized trials; C, only consensus opinion of experts, case studies or standard of care.
9 Similarly, there is increasing interest in the advantages of imbedding randomized clinical trials within the context of registries (cohort multiple randomized controlled trials).
Finally, multiple randomized controlled trials of interventions designed to test the hypothesis have shown very positive results in terms of improved health and reduced medical care costs.
Pooled-studies publications (PSPs) present statistical analyses of multiple randomized controlled trials without a systematic literature search or critical appraisal.
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