Sentence examples for multiple randomized double-blind from inspiring English sources

LDX has demonstrated efficacy in treating children and adults with ADHD in multiple randomized, double-blind, clinical trials.

Multiple randomized, double-blind, placebo-controlled trials have shown LDX to be an effective treatment for children, adolescents and adults with ADHD, with a tolerability and safety profile consistent with the known effects of psychostimulant therapy [ 9– 15].

In multiple large, randomized, double-blind studies of antipsychotic efficacy, patients identified lack of efficacy more commonly than medication intolerance as the reason they discontinued treatment, and patients' subjective assessment of lack of efficacy was corroborated by objective measures of psychopathology [ 3, 4].

This 4-week, multiple ascending dose, randomized, double-blind, placebo-controlled, Phase Ib trial enrolled 24 subjects.

The study was a 4-week Phase Ib multiple ascending dose, randomized, double-blind, placebo-controlled trial of AZD0530 in AD patients with Mini-Mental State Examination (MMSE) scorangingging from 16 to 26.

The first Phase III study of FTY720 in multiple sclerosis was a randomized, double-blind, parallel-group study, ie, TRANSFORMS (Trial Assessing Injectable Interferon versus FTY720 Oral in Relapsing-Remitting Multiple Sclerosis).

Hawker K, O'Connor P, Freedman MS, Calabresi PA, Antel J, Simon J, Hauser S, Waubant E, Vollmer T, Panitch H, Zhang J, Chin P, Smith CH; OLYMPUS trial group: Rituximab in patients with primary progressive multiple sclerosis: results of a randomized double-blind placebo-controlled multicenter trial.

For example, in the randomized, double-blind, Multiple Outcomes of Raloxifene Evaluation (MORE) trial of postmenopausal women with osteoporosis (n = 7,705), RLX decreased the risk of invasive breast cancer by 72% over 4 years compared with placebo (PBO) (relative risk (RR) 0.28, 95% CI 0.17 to 0.46) [ 65].

A phase 2, adaptive design, randomized, double-blind, multiple-center study of 198 adult patients with cellulitis or wound infections was conducted to evaluate an oral CEM-102 loading-dose regimen (1500 mg twice per day on day 1 followed by 600 mg twice per day) compared with oral linezolid (600 mg twice per day) administered for 10-14 days. 10-14 days

In this two-part, randomized, double-blind multiple-dose study in patients with OA of the knee, AMG 108 was well tolerated when administered SC (75 and 300 mg) or IV (100 and 300 mg).

The cardiac rhythm safety of moxifloxacin versus levofloxacin in high-risk elderly patients with CAP (eg, comorbid conditions and multiple medications) was recently evaluated in a randomized, double-blind trial (Morganroth et al 2005).