U, proteins up-regulated by CPT.
Among these 14 proteins, 7 were up-regulated and 7 were down-regulated, respectively, in spl5.
In addition, GA up-regulated a variety of cell growth/division, protein stability and defense proteins such as cell division cycle protein 48, molecular chaperones, and catalases.
Several genes up-regulated during muscle recovery encode protein regulating the cell cycle and mitosis.
Thus, multiple signaling inputs can up-regulate uPAR transcription in tumors.
There is evidence that multiple divalent metals (including Pb) bind to the Fe transport protein DMT-1 (Gunshin et al. 1997), and Fe deficiency is known to up-regulate this protein (Andrews et al. 1999).
Blocking one type of endocytosis may up-regulate alternative mechanisms, over-expression of mutant proteins may induce non-physiological cellular responses, and small GTPases may, via different sets of effectors, directly or indirectly control the activity of multiple endocytic pathways.
Perhaps most remarkably, protein aggregation and self-assembly has now been observed in multiple proteins that regulate the DNA damage response.
Here, the identification of multiple proteins regulating the levels of H3K56 acetylation in Drosophila and human cells allows future studies of this critical histone modulation which is implicated in cancer.
Multiple protein complexes regulate the Rag GTPases in response to amino acids, including GATOR1, a GTPase activating protein for RagA, and GATOR2, a positive regulator of unknown molecular function.
