Your English writing platform
Discover LudwigSuggestions(1)
Exact(3)
The 2A oligopeptide is emerging as a highly effective new tool for the facile co-expression of multiple proteins in a single transformation step, whereby a gene encoding multiple proteins, linked by 2A sequences, is transcribed from a single promoter.
The 2A oligopeptide is emerging as a highly effective new tool for the facile coexpression of multiple proteins in a single transformation step, whereby a gene encoding multiple proteins, linked by 2A sequences, is transcribed from a single promoter (de Felipe et al. 2006).
Since 2A mediates a co-translational 'cleavage' at its own C-terminus, sequences encoding multiple proteins (linked via 2As) can be concatenated into a single ORF: a single transgene.
Similar(57)
The tight junction complex consists of multiple adhesion proteins linking it to the cytoskeleton of the individual cells.
The picture emerging from these data is of a motor neuron festooned with multiple G-protein linked receptors each responding to a different class of neurotransmitter or peptidergic signal (Fig 8).
HERC2 is reported to associate with numerous proteins and likely has multiple ubiquitylation targets, including E6AP and proteins linked to DNA damage (Bekker-Jensen et al., 2010; Martinez-Noel et al., 2012; Moroishi et al., 2014; Galligan et al., 2015).
How are our proteins linked to our genome?
Foot-and-mouth disease virus 2A (F2andand "2A-like" sequences (e.g., Thosea asigna virus 2A; T2areare used widely for this purpose since multiple proteins can be coexpressed by linking open reading frames (ORFs) to form a single cistron.
Therefore, by enlisting multiple proteins as analytes that are mechanistically linked to breast cancer pathways or functional networks, we believe that the chance of success would be higher than the simpler conventional single-marker approach.
As individual membrane-bound proteins are cross-linked into larger clusters of multiple proteins diffusing together, their diffusion is slowed.
Lastly, we link scaffolds into super-scaffolds by examining contigs with multiple proteins which, in turn, are assigned to multiple contigs.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com