Sentence examples for multiple proteins involved from inspiring English sources
AMPK is a serine-threonine kinase that functions primarily as a metabolic sensor to coordinate anabolic and catabolic activities in the cell via the phosphorylation of multiple proteins involved in metabolic pathways.
Eukaryotic cells exposed to DNA damaging agents also activate important defensive pathways by inducing multiple proteins involved in DNA repair, cell cycle checkpoint control, protein trafficking and degradation.
TGFβ itself was reduced, as were multiple proteins involved in TGFβ signaling.
Multiple proteins involved in airway defense were detected in the LB proteome including antimicrobial and antioxidant proteins.
Human tankyrases post-translationally modify multiple proteins involved in processes including maintenance of telomere length, sister telomere association, and trafficking of glut4-containing vesicles.
Intriguingly, our proteomic analysis also found multiple proteins involved in Ras signaling downstream of EGFR activation as potential SUMO targets (Table 2).
Waanders et al. confirmed this at the protein level [24]: 24 h high glucose (16.7 mM versus 5.6 mM) activated glycolytic enzymes, and multiple ER proteins involved in protein folding and processing; also it activated ROS-scavenging proteins such as Prdx3 but down-regulated vesicle-associated proteins (Vamp2).
To understand if the observed reduction of BECN1 in AD patients is an isolated finding or if it could causes a more general disturbance of the autophagosomal system (similar to our in vitro findings) we measured multiple key proteins involved in autophagy (Fig. 7A) in human brain samples.
In addition, there are multiple assembly proteins involved in functional holoenzyme activity.
The remaining large isogroups with AS code for membrane proteins with multiple domains, proteins involved in protein degradation, or fulfilling regulatory functions.
Therefore, CALM/AF10 may strongly influence the levels of H3K79 methylation by interacting with both FHL2 and DOT1L; however, it will be very challenging to understand the complex interplay between these multiple interacting proteins involved in the regulation of histone marks.
