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These results indicate that a single SSB tetramer must interact simultaneously with multiple protein partners during some essential roles in genome maintenance.
LMO2 comprises two protein-binding LIM domains that allow LMO2 to interact with multiple protein partners, including LIM domain-binding protein 1 (Ldb1, also known as CLIM2 and NLI), an essential cofactor for LMO proteins.
The reason for this tight regulation may be understood in the context that TDP-43 interacts with multiple protein partners to form multiprotein complexes [6], [8], [43].
Methyl-CpG binding proteins represent an important class of chromosomal proteins that associate with multiple protein partners to modify surrounding chromatin and to silence transcription, providing a functional link between DNA methylation and chromatin remodeling and modification.
The fact that AK is a hub protein means that it interacts with multiple protein partners.
For example, in an enzyme superfamily, a domain may bind multiple protein partners in an enzyme complex or oligomeric unit.
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Surprisingly, we found that different point mutations that disrupt ANK domain binding to K9-dimethylated histone H3 had different phenotypes, suggesting that the histone H3 binding surface of the ANK domain may have multiple functions involving multiple interacting protein partners.
RACK1 has multiple protein binding partners and affects a variety of cellular functions.
Complex formation is one of the typical patterns in this graph and many cellular functions are performed by these complexes containing multiple protein interaction partners.
Addition of Bcl-2 inhibitors, antimycin or HA14-1, caused reduction of the bioluminescence signals (Figure 6C), demonstrating that three fragments of McLuc1, N-terminal ELuc and FLuc are useful for detecting interactions of a protein associated with multiple distinct protein partners.
The multiple interacting protein partners of DISC1 identify pathways and potential targets of relevance to schizophrenia, bipolar disorder, and potentially more generally for cognition and depression.
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multiple content partners
multiple protein cofactors
multiple protein sets
multiple protein isoforms
multiple protein databases
multiple protein products
multiple protein families
multiple protein aggregates
multiple protein bands
multiple sex partners
multiple protein targets
multiple protein sequences
multiple protein structures
multiple protein patterns
multiple protein classes
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