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The variety of CD44 functions is due to tissue-specific patterns of glycosylation of the extracellular portion, and to the multiple protein isoforms (CD44 variants, CD44v) generated by alternative splicing.
Pretranslational modification by alternative splicing, alternative promoter usage and RNA editing enables the production of multiple protein isoforms from a single gene.
In humans, multiple protein isoforms of CD45 are produced by alternative mRNA splicing of exons 4, 5, and 6 coding for the extracellular portion.
There are multiple protein isoforms of C/EBPβ and these differ in structure and function.
Alternative splicing is an effective mechanism for generating multiple protein isoforms with diverse functions from a single gene.
We confirmed that multiple protein isoforms were detected in both these groups consistent with the alternative splicing predicted by the whole exon array data: 64/190 (34%) AS+DE and 119/247 (48%) AS+CE proscripts.
Similar(16)
For each of Neurexin-1-α and Neurexin-1-β, multiple protein coding isoforms of NRXN1 have been identified, whose structure and functions are not well understood.
The homolog of p53 gene, p63, encodes multiple p63 protein isoforms.
However, methods are lacking for the quantitative screening of multiple S100 protein isoforms in clinical specimens.
Although multiple SW protein isoforms exist, they all differ significantly from the SDIC protein at both termini., Recently, the first axonemal dynein intermediate chain gene has been characterized in D. melanogaster.
Multiple insertions were often selected for a gene if they hit different parts of the gene (e.g., one insertion in a coding intron and one in a coding exon) or if they provided a way of differentially tagging multiple annotated protein isoforms.
More suggestions(15)
several protein isoforms
multiple splicing isoforms
multiple transcript isoforms
multiple protein products
multiple protein families
multiple protein subunits
multiple protein biomarkers
multiple protein bands
multiple protein kinases
multiple protein alignments
multiple protein molecules
multiple protein components
multiple protein variants
multiple protein species
multiple protein conformations
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