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Scaffolding proteins containing multiple protein interaction motifs are thought to provide the framework of the PSD through their interactions with both membrane proteins and the cytoplasmic proteins.
Previous studies have shown that Rolling pebbles (Rols)/Antisocial (Ants), a scaffold protein with multiple protein interaction domains, is involved in sustaining fusion beyond the bi/trinucleate precursor stage.
UNC-13/Munc13 UNC-13/Munc13 UNC-13/Munc13rotein interaction domains, and have been linked to nearly all asproteins presynapticontainse.
Therefore RACK1 is capable to interact simultaneously with several signaling molecules [ 8], suggesting the possibility of multiple protein interaction surfaces.
Syntrophins are adapter proteins that use multiple protein interaction domains to localize a variety of signaling proteins to specific intracellular locations.
LRRK2 also has multiple protein interaction domains suggesting that it may serve as a scaffold for the assembly of other proteins.
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Therefore, the use of McLuc1 with different N-terminal luciferase fragments allows precise and quantitative detection of multiple protein interactions in living cells.
This terminal repeat folds into the armadillo superhelical groove and allows homodimeric association with important implications for p115 mediated multiple protein interactions and tethering.
The formation of multiple protein interactions with DNA results in a decrease in protein-protein affinity and an increase in protein-DNA affinity with a net gain in overall stability for a protein-protein-DNA complex.
Clathrin is a three-legged molecule with a central hub domain from which three ∼190 kDa heavy chains are extended, each ending in an N-terminal seven-bladed β-propeller domain that allows for multiple protein interactions with various specificities between its blades [1].
WD40 domains can thus act as large interaction platforms for multiple protein interactions.
More suggestions(15)
multiple gene interaction
multiple actor interaction
multiple protein complex
multiple protein aggregate
multiple seam interaction
multiple protein sequence
multiple student interaction
multiple protein disulfide
multiple miRNA interaction
multiple injection interaction
multiple void interaction
multiple defect interaction
multiple carrier interaction
multiple cell interaction
multiple regression interaction
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