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Since SUMO modification participates in the regulation of multiple protein functions, repression of sumoylation may mediate a number of NO-related cellular events and pathological processes.
At best, this analysis can help to systematize the data on multiple protein functions.
Piatigorsky provided evidence for multiple protein functions for a single protein involved in different cellular mechanisms (Piatigorsky, 1992).
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Interference of multiple viral protein functions by a single-batch dsRNA should also be an ideal approach for RNAi-mediated fighting against viruses, especially the large and complicated WSSV.
These changes are not a consequence of a single protein but rather involve multiple proteins that function in pathways and networks.
A protein domain is a fragment of amino sequence that may appear in multiple proteins and function independently of the rest of amino acid chains.
Thus, our findings, together with the work of other groups, demonstrate that miR-124 may target multiple proteins that function spatiotemporally or in cooperation with different cellular processes.
Second, variable number of exons allow genes to produce, via alternative splicing, multiple proteins that function in different tissues and organs.
Thus, these data suggest that similar or identical N-glycan structures are expressed on multiple proteins that function as Dectin-1 ligands in these, and probably other, Dectin-1 binding tumor cells.
First, we employed Boolean logic to model regulatory interactions and simulated single and multiple protein loss-of-functions.
The BBS genes belong to multiple protein families and function cannot be defined based on homology; however, recent advances in molecular pathophysiology and animal models have helped to elucidate why 14 different genes can lead to the same phenotype.
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