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Insertional fusion between multiple protein domains represents a novel means of creating integrated functionalities.
Xyn10A was predicted to have multiple protein domains, which included a 317 AAs hydrolase domain, a 24 AAs linker region and a 37 AAs CBM1 domain.
This modular design strategy involves combining multiple protein domains with different functionalities into a single, modular polymer sequence, resulting in a multifunctional matrix with independent tunability of the individual domain functions.
Structural alignment can be complicated by the existence of multiple protein domains within one or more of the input structures, because changes in relative orientation of the domains between two structures to be aligned can artificially inflate the RMSD.
The raw data provided by KEGG were used to extract gene pairs with one or multiple protein domains, families or functional sites in common.
As reported previously [32], the RDP data demonstrated that the pspA gene had undergone extensive recombination, and the size of the recombination event could span one or multiple protein domains.
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A few protein resources like InterPro (Mitchell et al., 2015) and the Conserved Domain Database (CDD) (Marchler-Bauer et al., 2015) also combine multiple protein domain family databases like Pfam, SMART, TIGRFAM among others, providing higher sequence coverage compared with individual resources.
Marshalin exhibits multiple protein interacting domains including a CKK domain (DUF1781) at the C-terminus, a calponin homology (CH) domain at the N-terminus, and three coiled-coil (CC) and two proline-rich (PR) domains in the middle (Fig. 1C).
Group I mGluRs, including mGluR1 and mGluR5, have long intracellular C-terminal tails containing multiple protein binding domains and sites for phosphorylation and ER retention.
Previous studies have shown that Rolling pebbles (Rols)/Antisocial (Ants), a scaffold protein with multiple protein interaction domains, is involved in sustaining fusion beyond the bi/trinucleate precursor stage.
UNC-13/Munc13 UNC-13/Munc13 UNC-13/Munc13rotein interaction domains, and have been linked to nearly all asproteins presynapticontainse.
More suggestions(13)
multiple fluid domains
multiple protein variants
multiple protein factors
multiple protein products
multiple protein complexes
multiple protein interactions
multiple protein targets
multiple interaction domains
multiple protein subunits
multiple protein molecules
multiple protein bands
multiple protein alignments
multiple protein species
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