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Interestingly, it has been recently reported that PTEN is able to increase energy expenditure and improve organismal survival independently of its effect on cancer, thus suggesting that PTEN might have multiple protective functions [ 20].
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The involvement of EPAC1 in the activation of multiple protective mechanisms in one cell type highlights the importance of EPAC1 for the proper functioning of VECs and presents an intriguing model by which distinct cellular processes interact to initiate a co-ordinated program of protective, anti-inflammatory events.
It mediates several protective functions of HDL.
Keratin serves important structural and protective functions, particularly in the epithelium.
These dipeptides have several important protective functions.
The Protective Factors Survey assesses multiple protective factors against child maltreatment.
We believe this is due to the epithelium protective functions.
During neurodegenerative and neuroinflammatory disorders of the central nervous system (CNS), such as Alzheimer's disease (AD) and multiple sclerosis (MS), the protective function of the blood brain barrier (BBB) may be severely impaired.
Collectively, these studies have corroborated the protective function of Smad7 in attenuating TGF-β-mediated fibrosis in multiple organs.
Although a protective function is often taken for granted, recent studies show that body armor might comprise multiple functionalities and is shaped by trade-offs among these functionalities.
From tissue-specific RNAi experiments, we surmised that either the gene exerts its protective function in a tissue type we did not anticipate, or that it functions in multiple sets of tissues with redundant functions in host defense, thus knocking it down in only one or two sets of tissues was insufficient to recapitulate the whole body phenotype.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com