Sentence examples for multiple promoters and from inspiring English sources
Interestingly, these two proteins appear to have followed quite different evolutionary strategies in order to acquire novel functionalities, with OC following a gene duplication strategy while MGP variability was obtained mostly by the use of multiple promoters and alternative splicing, leading to proteins with additional functional characteristics and alternative gene regulatory pathways.
The human GGT1 gene has multiple promoters and is alternatively spliced leading to several mRNA isoforms [19].
The transcriptional regulation of c-MYC expression is complex and involves multiple promoters and transcriptional start sites, with P1 and P2 being the predominant promoters [18].
Transcriptional control of the CGL is rather complex as multiple promoters and alternative splicing are used to generate different mRNA species from both VAChT and ChAT genes [44].
Sno is present as a single copy in the human genome but multiple promoters and alternative splicing generate six distinct transcripts.
The presence of multiple promoters and an insulator in a transcription unit enables the PTS to display a promoter targeting activity.
26 of them are initial exons, which are supposed to be spliced by the multiple promoters mechanism, and 41 are 3'-terminal exons containing multiple poly(A) sites.
Many examples are known for clustering of bacterial SM genes in large operons that transcribe poly-cistronic messages from a single or from multiple promoters (Malpartida and Hopwood 1984).
Additionally, for genes that have multiple promoters, dsx and fru might regulate one or a subset of a gene's promoters, resulting in dimorphism in the abundance of isoform-specific transcript classes (transcript isoforms), which has been shown for a subset of genes that are sex-differentially expressed [ 30, 31], but has not been determined on a genome-wide level.
Our results showed that multiple promoters events and competing 3′ and/or 5′ splice sites events are likely to be the primary type of AS events in R2R3-MYB genes, which is in contrast to human and yeast AS events [ 37, 38].
About 18% of human genes have multiple promoters, which regulate and increase their transcriptional and translational potential [33].
