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Pretubulysin affects multiple processes implicated in cancer growth and metastasis, namely proliferation, long-term survival, anchorage-independent growth, anoikis and apoptosis induction by activation of caspases, Bid and Bax, cytochrome c release and degradation of the antiapoptotic protein Mcl-1.
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LPA has been found to be elevated in bronchoalveolar lavage (BAL) fluid of IPF patients, and through interaction with its cell surface receptors, it has been shown to drive multiple biological processes implicated in the development of IPF.
Another reason for this debate stems from the multiple and complex processes implicated in achieving UHC.
Current theoretical models suggest that the skills, insights, and self-awareness learned through yoga and mindfulness practice can target multiple psychological, neural, physiological, and behavioral processes implicated in addiction and relapse.
Many cellular processes implicate large protein networks.
iNKT have been implicated in multiple processes, including microbial immunity, tumor rejection, autoimmunity, atherosclerosis and allergy [2], [3].
ABL1 has been implicated in multiple processes including cell division, cell adhesion and cellular stress response.
Ubiquitin proteases are implicated in multiple processes, including the reversal of ubiquitylation, which functions to prevent degradation or to modify substrate activity.
Furthermore, RSC has been implicated in multiple processes such as kinetochore function and recruitment of cohesin along chromosome arms (Hsu et al. 2003; Huang et al. 2004).
The amino acid, osteocalcin, and divalent calcium ligand specificity of this receptor and its wide tissue distribution implicate GPRC6A multiple processes.
MicroRNAs (miRNAs) have been implicated in regulating multiple processes during brain development in various species.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com