Sentence examples for multiple probesets that from inspiring English sources

As a summary statistic for multiple probesets that match to the same entrez gene identifiers we used the median expression value.

This can result in probesets targeting transcripts of multiple genes due to low probe specificity, probes that do not map any of the known transcripts [ 41, 42] or multiple probesets that map the same gene [ 39, 40], requiring the development of methods used for the validation of existing probes and for probeset redefinition [ 41, 42, 96].

By further characterization of the multiple probesets that interrogate some of the genes represented on the Affymetrix arrays, it may be possible to further reduce the number of hypotheses tested by testing for evidence of differential gene-level rather than probset-level hybridization.

This suggests either that a subset of the multiple probesets that interrogate a particular gene have a reduced ability to detect differential expression or that it is more difficult to reliably detect the expression of those genes that are interrogated by multiple probesets.

The output can be further filtered so as to exclude multiple probesets that map to the same gene or to the same location.

Unigene ids associated with multiple probesets that exhibit different patterns of expression were removed from the dataset, ensuring unambiguous data that could be easily used in subsequent enrichment analyses.

They redefined ∼37% of the probes and identified more than 5,000 probesets that detected multiple transcripts.

For probesets that correspond to multiple genes, the gene with the smallest absolute value of 3' distance was chosen.

Importantly, using the gene name as an identifier, it is clear that multiple probesets are present for many genes but that these replicate probesets may not always generate similar detection rates.

and varying experimental conditions (e.g. transfected/transduced cells, cytokine stimulated, cells under hypoxic conditions, ultraviolet treated cells, cells treated with chemotherapeutics or non cytotoxic drugs etc).. Probesets that were available on both platforms were converted to official gene symbols, averaging expression values of multiple probesets targeting the same gene.

The PPARα-dependently regulated probesets were then identified by extracting those probesets that were only significantly regulated in both Contrast 1 and Global Contrast, and subsequently corrected for multiple testing.