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For genes with multiple probes, final expression values were the mean of the expression levels for multiple probes.
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Multiple probes per single gene were averaged to produce a final set of 14,411 genes.
We then filtered out multiple probes representing the same gene and probes representing uncharacterized locations, giving a final list of 223 individual genes.
In cases with multiple probes per gene the most variable probe was selected, resulting in 18,295 unique genes.
In cases with multiple probes per gene the most variable probe was selected, resulting in 18,295 unique coding genes.
Simultaneous imaging of multiple probes or biomarkers represents a critical step toward high specificity molecular imaging.
Instead of using the average of multiple probes in the promoter region, we also compared the raw β-value of each probe between the two groups.
For genes with multiple probes, the average values of the probes were used.
The rest of the genes represented by multiple probes showed consistent expression patterns among the probes.
In the case of genes with multiple probes, the result for the probe with the greater signal intensity was chosen.
We only tested multiple probes in the current study.
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