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15 In the present study, the incidence of multiple primaries was 6.1% for patients initially diagnosed between 2005 and 2012.
For the relative risk of any cancer, the first cancer reported for patients with multiple primaries was used in the time to event analysis.
Considering all cancer patients, the risk of developing multiple primaries was much higher for those presenting initially with stage 0 or stage I disease.
24 More than one quarter (28%) of the population surviving childhood cancer experienced additional cancer primaries, and within 20 years from diagnosis of the index primary, the estimated cumulative incidence of multiple primaries was reported to reach 47%.
Further, there was no difference in survival between single and multiple primaries when survival with multiple primaries was calculated from the date of diagnosis of the second primary rather than from the date of the initial cancer diagnosis (P=0.05956, Figure 6).
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Trusted surrogates like Sarandon help spread the senator's message across the country, especially when multiple primaries are crammed within hours of each other and Sanders can't physically appear in each state that is voting.
For breast, lung and colorectal cancers, within-site multiple primaries are expected; in contrast, for prostate cancer, multiple primaries are not usual.
In situ carcinomas were included, whereas death certificate only and multiple primaries were excluded.
The worst survival rate was for simultaneous concomitant multiple primaries, being a median of 1.9 years.
Demographic data on single versus multiple primaries are shown in Table 1.
Multiple primaries were handled by the default set by the SEER*STAT program.
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