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Many different but equally predictive gene lists have been identified for predicting prognosis [ 11], and it remains to be seen whether there are multiple predictive markers of response to different therapies.
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Both groups were assessed against Tasker's criteria and a multiple regression model used to identify predictive markers with length of ventilation as the dependent variable.
In the context of multiple treatment possibilities, the identification of predictive markers of response to chemoradiotherapy treatment is a challenging approach for drug selection in order to obtain the best clinical benefit while minimising the side effects for each patient.
In addition, because a consensus has not been reached regarding how often endoscopy follow-up should be performed after ESD, there is an important need for predictive markers to identify patients with an increased risk of multiple recurrences of EGC.
The observation that chemo-resistant tumors are significantly more diverse molecularly than chemosensitive tumors implies that multiple resistance mechanisms may be active, thus limiting the sensitivity and accuracy of predictive markers of chemotherapy response.
Taken together, results from multiple phase III studies support the use of angiome analyses to identify potentially useful prognostic and predictive markers.
Multiple predictive factors for operative intervention were identified.
These markers could be useful as markers for EMT in breast cancers and may serve as predictive markers for designing customized therapy in the future.
In this paper, design strategies for clinical trials aimed at disclosing predictive markers are discussed.
Second, study of idiopathic RBD allows prospective testing of other predictive markers of neurodegeneration.
Additional predictive markers of treatment sensitivity and resistance could allow rapid identification of effective treatments and avoidance of futile therapy.
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