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Within the CYCLIN D/RBR pathway there are multiple potential targets, amongst which CDK inhibitors (KRPs) and E2F transcriptional factors are additional relevant targets.
All the 70 or so WD-40 units of the NWD family members, the basic elements of the WD recognition domain, are multiple potential targets for mutagenesis which per se might already be a significant enhancement of mutation supply.
However, since task requirements were not manipulated, Drew and Vogel's [26] study does not address whether individuation operates in a mandatory fashion determined only by target numerosity, or whether its operation over multiple potential targets depends on task demands.
Curcumin and its analogs have multiple potential targets [ 27].
The mechanisms that link programmed changes in expression of miRNAs, each with multiple potential targets, to metabolic phenotype and disease susceptibility are likely to be exceedingly complex.
Thus there are multiple potential targets for cancer therapy, resulting in an increasing need for distinct therapeutic agents and their combinations.
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Suboptimal hybridizations: I NTARNA can predict multiple potential target sites per sRNA.
Thirty-four of these va-miRNAs had multiple potential target sites, for instance, va-miR006 which has 103 target sites tops the list, followed by va-miR081 and va-miR003 with 59 and 33 target sites respectively.
Wnt proteins, however, constitute a large family of proteins that have been variously attributed pro- and anti-fibrogenic properties [ 35– 38] and which likely have multiple potential target cells and mechanisms of action during chronic liver disease.
The action of PPARβ/δ involves multiple potential target tissues (11), appearing to increase HDL cholesterol levels and to reduce postprandial triglyceride levels by increasing their clearance (12), leading to potentially beneficial changes in fasting triglyceride, apoB, LDL cholesterol, insulin, liver fat, and urinary inflammatory markers (13).
This highlights multiple potential therapeutic targets, and optimizing the therapeutics for each of these targets is the goal of ongoing research and development.
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multiple potential predictors
multiple potential explanations
multiple potential rates
multiple potential reasons
multiple potential bidders
multiple potential answers
multiple potential products
multiple potential suitors
multiple potential anticarcinogens
multiple subcellular targets
multiple potential steps
multiple potential causes
multiple potential consequences
multiple potential lead-users
multiple potential violations
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