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The key problem of cooperative MAC protocols is how to select the best helper from multiple potential candidates, i.e., identifying the condition that the best helper must satisfy, the criteria for choosing a helper, and when to cooperate.
Well-designed large prospective trials are needed to identify key genes among the multiple potential candidates that can help a clinician make real-time treatment decisions in respect to a particular regimen depending on a patient's pharmacogenetic profile.
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In silico examination of the mouse FoxO3 locus showed multiple potential candidate sequences containing TR-binding elements, although none was evolutionally conserved, and ChIP assays failed to identify functional relevance under our experimental conditions.
The ability to investigate the genetics underlying disease phenotypes at a genome-wide level will result in more rapid disease gene identification, as genome-wide analyses can return multiple potential candidate genes simultaneously, rather than verifying or refuting the implication of individual genes in a sequential way.
Under such circumstances, MCPC allows identification of any one potential target from multiple possible candidates (e.g. 1 of 15 or 1 in 31) in a single reaction.
One study demonstrated a positive association between extraversion and potential candidates' multiple mini-interview performance and between extraversion/agreeableness and their acceptance offers [ 40].
This paper investigates a feasible mission scenario among the potential candidates of multiple flybys and sample return missions.
3. Patients with disseminated multiple metastases, who are not potential candidates for resection and who present with mostly asymptomatic, not rapidly progressing disease.
The total number of potential candidates that met these multiple criteria was 33 (30 new) (Figure 1A); this number was experimentally amenable.
These included several multiple-stress-inducible genes that could represent potential candidates for use in the engineering of stress-resistant plants.
However, this focusing is not trivial, as every chronic disease is studied by multiple research groups that customarily formulate multiple competing hypotheses [ 7], thus, populating the lists of potential candidates with thousands of entries.
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