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Second, genome bins that clearly consisted of multiple populations were re-binned using MetaBAT specifying increasingly more stringent sensitivity parameters, until 'contamination' in each bin was minimized.
In this paper, multiple populations were introduced to obtain sets of parameter values that optimize the objective function.
These multiple populations were mostly found homogeneously distributed within the necrotic core of granulomas with a smaller proportion in the surrounding acellular rim.
For each species, animals of both sexes from multiple populations were used.
Each population was tested as a separate experiment in environments where multiple populations were evaluated.
Multiple populations were analysed for all but three species (Ranunculus pygmaeus, Potentilla frigida and Saxifraga bryoides).
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Comparison of these initial studies indicates that broad systematic comparisons of multiple populations are required to provide an unbiased scan for loci under locally varying selection.
The sample set from England showed the greatest degree of deviation from HWE (significant at 3 loci for heterozygote deficit) which could be because of the Wahlund effect (seen when multiple populations are grouped together as one; Wahlund, 1928).
Therefore, in the initial population stage, different individuals in multiple populations are randomly assigned different numerical sizes.
For ease of notation, we consider a one-population model ((M=1)); the generalization to multiple populations is then straightforward (see Sect. 3.4).
Sampling additional individuals from multiple populations is likely to increase observations of polymorphism.
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