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By using multiple polymorphisms throughout the genome, SA probabilistically assigns sampled individuals to these latent subpopulations.
By testing multiple polymorphisms throughout the genome, only some of which are pertinent to the disease of interest, the degree of overdispersion generated by population substructure can be estimated and taken into account.
Similar(58)
Six promoters had multiple polymorphisms that failed HWE tests.
Initial studies by our group indicated multiple polymorphisms in these other regions, many of which were not in significant linkage disequilibrium with the coding polymorphisms [9] [11].
Among the multiple polymorphisms of the VDR gene, FokI polymorphism (rs10735810) is the only one without any link to other VDR polymorphisms and is the sole polymorphism that leads to two different VDR protein products [ 25, 26].
Multiple polymorphisms were examined in the IL10, TNFRSF6, TNF, TGFB1 and MBL2 genes by PCR haplotyping.
Few previous studies have examined multiple polymorphisms in relation to PH associated with COPD.
Microarray has become a powerful technique to screen genes for multiple polymorphisms on hundreds of samples.
One of the few genes showing multiple polymorphisms between these strains is ABR072C.
Multiple polymorphisms and metabolites were considered, and several multivariate regression models were tested.
TYK2 promoter variant with multiple polymorphisms was identified in the Japanese.
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