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Equal numbers of shared genes from the distributed set were shared by one or multiple plasmids, indicating that both single and multiple genetic exchange events among plasmids and chromosomes occurred during evolutionary history.
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Sequence of the 10 mutant plasmids indicated that each plasmid contained single or multiple mutations in the rep gene or the flanking regions.
Sequence variability, presence of mosaic structures of plasmids combining modules from various origin and chimeric plasmids indicates a high genetic diversity of enterococcal plasmids [ 21, 23- 26].
Previous phylogenetic analyses of chlamydial plasmids indicated that their evolutionary lineage includes plasmids from other chlamydial species [ 29].
FST sequences that aligned to multiple, non-repetitive genomic regions and/or additional regions of the pSKI015 plasmid indicated multiple, imprecise or complex T-DNA integrations.
The GC content, GC skew, and the length of the plasmid indicates multiple changes in the sequence of pPDL2 either due to acquisition of foreign DNA or rearrangement of its own sequences.
As multiple plasmids were found in majority of our bacterial isolates, higher chance of β-lactamase gene mobilization existed in eastern Indian patient population indicating higher bacterial clonality for blaTEM carriage.
The method described here could also be particularly useful in curing individual plasmids from strains that carry multiple plasmids.
These organisms possess multiple plasmids.
Many bacterial strains contain multiple plasmids, but the relationships between bacterial plasmids and chromosomes are unclear.
All 4 isolates contained multiple plasmids (data not shown).
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