Sentence examples for multiple phenotypic hallmarks from inspiring English sources

Therefore, these results suggest the striking conclusion that multiple phenotypic hallmarks of brain aging are generated by aging-related modifications (weakening or strengthening) of selective GC signaling pathways.

41– 43 The phenotypic hallmarks of this disease include multiple facial papules, trichilemmomas, oral papillomas, and macrocephaly, though there are varied expressions of the disease even among families.

Pleiotropy occurs when a single genetic loci influences multiple phenotypic traits.

Since this study employs multiple phenotypic scales, the potential exists for type I errors.

Morphological and phenotypic hallmarks of EMT were identified in the chemoresistant cells.

The uterotrophic response also provides well characterized phenotypic hallmarks that facilitate the interpretation of gene expression changes and their function.

Finally, senescent cells undergo multiple phenotypic and functional changes.

Some alleles were associated with multiple phenotypic classes.

Such associations, when observed, still require rigorous validation to ensure that exposures are unequivocally linked to the development of both cancer and accompanying phenotypic hallmarks.

These genes may provide important targets for intervention in GA, evidenced by their role in promoting invasion and proliferation, key phenotypic hallmarks of cancer cells.

Recent work has revealed that rapamycin, an mTOR (mammalian target of rapamycin) inhibitor, significantly reduces the phenotypic hallmarks of progeria in HGPS cells by down-regulating progerin [ 15].