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There are thus multiple phenotypic axes along which taxa may diverge during speciation, with varying opportunities for environmental influence.
Our results therefore highlight the fact that speciation is the combined result of divergence along multiple phenotypic axes.
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Finally, at the organismal level, pleiotropy is detected when changes in a single locus lead to multiple phenotypic effects.
In the initial formulation of FGM, all phenotypic axes intersect at the origin of each axis.
Pleiotropy occurs when a single genetic loci influences multiple phenotypic traits.
Since this study employs multiple phenotypic scales, the potential exists for type I errors.
For example, the gene ybaL, which was mutated in 65 of 115 lines, does not associate with any phenotypic axes.
Finally, senescent cells undergo multiple phenotypic and functional changes.
Some alleles were associated with multiple phenotypic classes.
The incorporation of measurement error in our model comparisons did not lead to any bias towards parameter-rich models and the four phenotypic axes present no changes in the preferred models when accounting for it (Additional file 1: Table S7).
Fig. 1 Flexible architecture of the Valiance X12 enables multiple independent axes of motion.
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