(AMR), possesses multiple pharmacological activities.
Triptolide has multiple pharmacological activities including anti-inflammatory, immune modulation, antiproliferative and proapoptotic activity.
The present study was undertaken to determine the multiple pharmacological activities of VAR in neurodegenerative preclinical models.
As a well-known Chinese Materia Medica Rhizoma Anemarrhenae has multiple pharmacological activities including antipyretic, anti-inflammatory, anti-diabetic actions, etc.
Many of these agents are hybrid molecules, which are designed through concept of molecular hybridization and have shown multiple pharmacological activities.
Based on the above evidences, we reason that the new synthetic ligustrazinylated derivatives possess multiple pharmacological activities such as neuroprotection and protection against vascular endothelial cell injury, suggesting that they may be more efficacious than either a neuroprotective agent or vascular protective drug alone.
Sideritis scardica (Mountain Tea), an endemic plant of the Balkan Peninsula, is generally acknowledged as a very popular consumed beverage with multiple pharmacological properties including antioxidant activity.
Among berberine multiple pharmacological actions, anti-inflammatory activity has been extensively studied [ 23].
It has multiple pharmacological effects including; antimicrobial activity against 54 microorganisms [ 19- 21], inhibition of intestinal ion secretion and smooth muscle contraction, inhibition of ventricular tachyarrhythmia, reduction of inflammation, stimulation of bile secretion and bilirubin discharge [ 22].
Phytochemicals screening have confirmed the presence of flavonoids, saponins and terpenoids, all these classes of phytochemicals are responsible for multiple pharmacological actions including anti-inflammatory activity [ 24– 26].> -wrap-foot> > -wrap-foot> > -wrap-foot> ethylthyl acetate fraction, PGE 2 prostaglandin E2.
Previous studies have shown that shikonin has multiple pharmacological properties, such as anti-proliferative activities, anti-angiogenic [ 2, 3], anti-inflammatory [ 4, 5], anti-virus [ 6], antioxidant [ 7], anti-adipogenesis [ 8], immunomodulatory effects [ 9], wound healing [ 10] and others [ 11, 12].
