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Space flows freely up and down staircases and ramps, creating multiple pathways within what amounts to an interior landscape: a fixed but flowing garden of sculptural void.
Bispecific antibodies (BsAbs) are designed to engage two antigens simultaneously, thus, effectively expanding the ability of antibody-based therapeutics to target multiple pathways within the same cell, engage two separate soluble antigens, bind the same antigen with distinct paratopes, or crosslink two different cell types.
Usually, cell proliferation and differentiation are controlled by a series of specific mitogenic and antimitogenic signals that drive multiple pathways within cells.
The presence of transcription regulatory proteins may affect multiple pathways within recipient cells, potentially altering any number of cellular outcomes.
Here, we have explored the addition of an agent to docetaxel, which exploits multiple pathways within the prostate cancer tumor microenvironment.
Similarly, there is a greater than expected proportion of enzymes, especially those within multiple functions or involved in multiple pathways, within the essential gene groups [ 65].
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This diversity of isoforms and mechanisms enables GCs to regulate multiple pathways independently within the same tissue or cell.
CaMKII is activated by multiple pathways and, within the CM, primarily acts by phosphorylating the main components of the calcium handling machinery and, as such, has a clear relevance in the pathophysiology of CPVT.
Our study aimed to systematically analyze the time-dependent variation in the expression of multiple pathways and networks within 24 h after cerebral ischemia-reperfusion injury.
The functional variability of genes within multiple pathways was also demonstrated.
They have an essential role in the signal transduction networks that leads from the perception of stress signals to the expression of stress-responsive genes, and, as opposed to most structural genes, tend to control multiple pathway steps within a transcriptional cascade [ 25].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com