Sentence examples for multiple pathways underlying from inspiring English sources

For example, the ability to provide effective topical therapies that target multiple pathways underlying retinal neovascularization and edema could further improve the current management strategies for DR. Development of such therapies requires substantial basic and experimental studies, for which appropriate animal models of DR are essential.

Multiple pathways underlie decreased β-cell function and mass, some of which may be shared, with reduction in mass, perhaps a consequence of processes that initially caused dysfunction.

Multiple pathways underlie decreased β-cell function and mass, some of which may be shared and may also be a consequence of processes that initially caused dysfunction.

We here review the multiple signaling pathways underlying each of the three main morphological types of cell death – apoptosis, autophagic cell death and necrosis – emphasizing their importance in the neuronal death that occurs during cerebral ischemia and hypoxia-ischemia, and we analyze the interactions between the different mechanisms.

A number of recent studies have focused on the role of miR-145 in multiple cellular pathways underlying carcinogenesis.

Given the multiple interactive pathways underlying AKI, it might be a mistake to concentrate therapeutic effects on one single part of the interrelated cascades.

In the sugar signaling pathway, HXK1 is a glucose sensor that modulates gene expression and multiple plant hormone-signaling pathways underlying sugar sensing and signaling in plants (Pego et al. 1999; Jang et al. 1997).

Here we review the multiple pathways that underlie effective lung immunity in health, and discuss how these may be affected by external environmental factors and contribute to chronic inflammation during disease.

To answer this question, microarray data originating from two experimental procedures were analyzed by multiple methods employed for identification of consensus differences in pathways underlying CRC development through the adenoma-carcinoma sequence.

It has also been suggested that genes or entire genetic pathways underlying the loss of structures may be maintained because they serve multiple functions or pathways, and can be re-expressed subsequently [ 42].

The integration of multiple omics technologies will be needed to gain a deeper understanding of the mechanisms and pathways underlying transplant outcomes.