Sentence examples for multiple pathways therefore from inspiring English sources

In addition, pesticide levels in both residential dust and biomarkers aggregate over multiple pathways; therefore, independent contributions from each pathway are not easy to discern.

These results indicate that different agents may allow for simultaneous Puma induction via multiple pathways; therefore, lowering the threshold proapoptotic activity is required for apoptosis induction.

Recent reports have demonstrated that NF- κB indirectly inhibits ROS generation (Sakon et al, 2003; Kamata et al, 2005); however, the intracellular ROS balance may be regulated by multiple pathways, therefore, it is still uncertain whether ROS generation is due to NF- κB/I- κB inhibition cascade in bortezomib-treated cancer cells.

Orally administered HSP90 inhibitors may open new perspectives in the treatment of these lymphoma by targeting multiple pathways and therefore eliminating the danger of resistance development observed in single targeted therapies as with imatinib mesylat.

Diabetes is a complex disease involving many organ systems and multiple signaling pathways; therefore it is necessary to investigate its causes and effects in vivo.

Many genes were included in multiple pathways and we therefore defined the metric Pathway Maps as the number of pathways onto which a given gene is assigned across all resources used in ensemble construction.

41 Therefore, multiple pathways can regulate netrin-1 expression in the context of inflammation.

Therefore, multiple pathways can be explored to further understand the role of inflammation in the orchestrated response to balance neuroprotection and neurotoxicity in the diabetic retina.

It is worth mentioning that BRAF mutation affects mainly one signalling pathway for cell proliferation, whereas KRAS mutation affects multiple pathways (Fig.  1); therefore, the impact of BRAF mutation is less than that of KRAS mutation.

In patients with mutant BRAF melanoma a combination of a selective RAF inhibitor with an HSP90 inhibitor may, therefore, inhibit multiple pathways involved in resistance.

Therefore, activation of multiple pathways is a necessary condition for proper midgut regeneration (Supplementary Figure S8).