Sentence examples for multiple pathways representing from inspiring English sources

On the other hand, when a disease has defects in multiple pathways representing distinct biology, a pathway-guided combination therapy may be employed in the clinic.

However, there are also multiple pathways representing metabolic networks including pyrimidine, purine, protein ubiquitination, glycolysis/gluconeogenesis, aryl hydrocarbon receptor signaling and aminoacyl-tRNA biosynthesis.

As the core component of an approved antiosteoporosis agent, strontium takes its effect on osteoblasts at multilevel through multiple pathways, representing a good example in revealing and exploring anabolic mechanisms.

In particular, we have found that a large portion of the central cellular metabolism consists of multiple pathways represented by genes with strongly similar phyletic vectors, so that a probabilistic model of one pathway was not able to distinguish between this pathway and other subsystems.

The sub-thalamic auditory system consists of chains of nuclei in the brainstem giving rise to multiple parallel pathways represented in mirror image about the midline.

Crustaceans bear multiple parallel chemosensory pathways represented by different populations of unimodal chemosensory and bimodal chemo- and mechanosensory sensilla on the mouthparts, the walking limbs and primarily on their two pairs of antennae.

While increased signaling via VDR, AP-1, IL-6 and AR in the optic nerve can be broadly interpreted as a cytoprotective, activation of ephrin A4 receptor and multiple pro-inflammatory pathways represent potentially cytotoxic events, which are conducive to oxidative stress and possibly harmful to CNS neurons and their axons.

Various technical differences have been proposed to account for this discrepancy, but others have noted that if one looks beyond the genes to the pathways they represent, multiple pathways can be found in common between the signatures, indicating that the signatures and their predictive powers may converge on the same underlying biology [ 6].

4 Targeting intracellular pathways represents a novel approach of inhibiting the effects of multiple cytokines.

The data presented here suggest that the intersection of the Shroom3 and PCP pathways represents a model of how the simultaneous reduction of multiple pathways can cause NTDs.

These pathways represent an important shift in conservation strategy.