Sentence examples for multiple pathways leading from inspiring English sources

The rupture of HK VDAC1 protein complex provides a therapeutic opportunity, as this association appears to protect tumor cells from mitochondrial outer membrane permeabilization, an event that marks the point of no return in multiple pathways leading to cell death.

In conclusion, these data are compatible with the concept that chemical inhibition of complex I activates multiple pathways leading to cell injury; among these, peroxynitrite formation may be the most critical.

Multiple pathways leading to the formation of the C28 sterol ergosterol vary according to the sequence of double bond transformations.

Re-programming of gene expression in chronic alcoholics apparently involves transcription factors that are responsive to the primary effects of ethanol, and that regulate multiple pathways leading to neuropathology and neuronal dysfunctions.

Although some neuronal loss still occurred, the SIV-infected microglia supernatant may trigger multiple pathways leading to neuronal death, with the impairment to autophagy constituting only one of the pathways.

These results suggest that TrpC3 is a common element in multiple pathways leading to the induction of cardiac hypertrophy and that it plays only a minor role in regulating BNP levels in non-hypertrophic ventricular myocytes.

This may also permit the development and manufacture of polyclonal antibodies that recognize multiple surface proteins and simultaneously activate multiple biochemical pathways leading to cell death.

The Ras gene mutations were thought to activate multiple signaling pathways leading to cell proliferation (Maruta & Burgess, 1994).

The finding that the associations between HBP and markers suggestive of increased permeability were weak could reflect the complex pathophysiology of sepsis with multiple redundant pathways leading to increased permeability [1].

The plethora of physiopathological events associated with brain ischemia are regulate through multiple signaling pathways leading to the activation of oxidative stress process, Ca2+ dyshomeostasis, mitochondrial dysfunction, proinflammatory mediators, excitotoxicity and/or programmed neuronal cell death.

In our scenario, folding is characterized by a milestone event followed by multiple different pathways leading to the native state.