Climate change affects ecosystem carbon dynamics through multiple pathways, including altering biogeochemical cycles (e.g., productivity), disturbance regimes (e.g., fire), and land use [1,2].
In conclusion, our integrated network analysis revealed that JA and UA treatments individually affected multiple pathways, including IGF-1 signaling.
AS exposures remarkably influenced multiple pathways including RNA transport, the spliceosome, RNA degradation, p53 signaling and MAPK [123].
Here, we report that RBP-J, a DNA-binding protein that integrates signals from multiple pathways including the Notch pathway, is critically involved in polarization of M2 macrophages.
However, beyond radicals, metal ions can disrupt normal cell and tissue function through multiple pathways including interactions with proteins and other biomolecules and disruption of membrane potentials [4].
Proteins involved in multiple pathways, including jasmonic acid synthesis proteins and oxidative stress-response, showed significant changes in expression pattern in response to BPH feeding.
These findings suggest that multiple pathways, including intracellular fatty acid metabolism, may be strictly regulated by lysine acetylation in oleaginous yeast.
However, some exception have been documented wherein multiple pathways including caveolae-mediated endocytosis were observed for internalization of strong cationic surface charged nanomaterials [105].
Pathway analysis revealed multiple pathways including Jak-STAT, TGF-beta, PI3K-Akt and MAPK signaling pathway that are correlated to colorectal cancer.
In a tumor microenvironment, Snail can be activated through multiple pathways, including HIF1, HIF2, and Notch in response to hypoxia as well as NF-κB and TGF-β in response to inflammation [28,29].
Our results showed that BPH feeding induced significant changes in the abundance of proteins in phloem sap of rice involved in multiple pathways, including defense signal transduction, redox regulation, and carbohydrate and protein metabolism, as well as cell structural proteins.
