Complement factor I is a soluble serine protease that regulates multiple pathways in complement activation.
Previous studies have implicated only isolated genes in the development of chronic rejection and have not examined multiple pathways in an individual concurrently.
These studies related to the abnormal vein patterning caused by mutation of particular genes provide some clue as to how Kranz anatomy is regulated and suggest involvement of multiple pathways in development of the Kranz pattern.
The basic science studies will demonstrate how SCS acts on various pain syndromes and diseases via multiple pathways in the central nervous system as well as in somatic structures and visceral organs.
Since emerging evidence indicates that TAG synthesis in microalgae operates through coordinated crosstalk between multiple pathways in diverse subcellular destinations including the endoplasmic reticulum and plastids, we discuss new experimental studies and models that incorporate these findings for discovering key regulatory checkpoints.
Unlike with CTLA-4, the TcR employs multiple pathways in the activation of PKB/AKT [36].
First, a single hairpin-encoding TE locus may follow multiple pathways in a competitive manner.
One cautionary note is the effect of calmodulin inhibitors, such as TFP, on electrostatic surface potential, which could interfere with multiple pathways in addition to calmodulin [18].
This information is encoded and transferred via multiple pathways, in different time-scales, and is typically processed in parallel by multi-component networks.
This investigation provided insight into the pathophysiology of cardiac remodeling and the potential role of SERCA2a normalization in multiple pathways in diabetic cardiomyopathy.
The implication of multiple pathways in PMA-induced HB-EGF shedding led us to examine the mitogen-activated protein (MAP) kinase cascade, which in some cell types appears to be essential for the PMA response [23], [24].
