Sentence examples for multiple pathways at from inspiring English sources

Emergence of drug resistance mechanisms to specific TKIs, such as gefitinib and erlotinib, suggests that more sophisticated chemotherapeutic paradigms that target multiple pathways at the same time will be required to effectively treat this disease.

In theory, such an approach may abrogate or delay resistance by disrupting multiple pathways at once.

Furthermore, it achieves a new level of complexity by considering multiple pathways at once in a comprehensive manner.

The competence of miRNAs to regulate multiple pathways at various checkpoints makes them in theory useful as therapeutics.

Information concerning the putative binding sites are provided in Additional file 6. MiRs can regulate many target genes and modulate multiple pathways at the same time.

Studies have signified that they can alter multiple pathways at the same time and inhibit tumour promoting pathways while also activating tumour suppressor pathways [ 7, 8].

The fact that multiple PKC isoforms play a role in PMA-induced HB-EGF shedding in HT1080 cells is in line with previous findings, indicating that PMA-induced shedding of EGFR-ligands implicates multiple pathways, acting at the level of both protease and substrate [34], [35], [36].

PF stimulation probably activates multiple pathways; even at low intensities it should not be regarded as a selective assessment of cerebellar function unless stringent controls can confirm the absence of confounding activity in other pathways.

51% of the 206 species studied and 82% of the 61 species with putative multiple pathways have at least one complete chemotaxis operon (containing cheA, B, R, W and Y).

While the molecular mechanism of adiponectin is not completely understood, adiponectin has been linked with multiple signaling pathways at multiple sites (22– 22).

When multiple pathways are selected at the same time, the view will show all unique gene components within selected pathways.