Sentence examples for multiple pathways as from inspiring English sources
However, less is known about the genetic mechanisms of aging in genome wide, particularly at the level of multiple pathways as well as the regulatory networks during aging.
Our results support the view that the single protein unfolds along multiple pathways as suggested in recent theoretical studies.
Ataxin-1 is involved in multiple pathways as suggested previously and each of these might contribute to SCA1 pathogenesis [26].
EhCaBP1 is also thought to be involved in multiple pathways as it binds a variety of target proteins observed by immunoprecipitation and mass-spectrometric studies [5, unpublished observation].
Another feature of this analysis is that one pathway is often compensated by multiple pathways, as exemplified by cytoskeletal components (necessary for moving complexes through the cell) and the two mannan polymerase complexes that were both identified as belonging to the same group of proteins compensating chitin synthesis.
Furthermore, it is also important to analyze proteins involved in multiple pathways, as they may possibly act as linkers among these pathways.
Through site-specific dephosphorylation, constitutively active PP2Ac disrupts the signal-promoting TLR4-MyD88 complex and broadly suppresses the activities of multiple proinflammatory/proapoptotic pathways as well, shifting proinflammatory MyD88 signaling to a prosurvival mode.
Previous studies on mechanism underlying the regulation of autophagy in cancer cells showed that autophagy was regulated by multiple signaling pathways as diverse as the class III PI 3-kinase, and the protein kinases mTOR, ERK, and p38.
Therefore, it is likely that the mechanism(s) of ovarian cancer growth and metastasis will involve multiple biochemical pathways, as has been concluded for pancreatic and breast cancers [ 1, 26].
Combining circuit theory and LCP allows archaeologists to produce richer models of past movement by appreciating scenarios where multiple pathways are important as well as scenarios where optimum single travel routes have priority.
Depression is thought to be unpinned by multiple pathways, such as inflammation, oxidative and nitrosative stress, as well as a decrease in antioxidant levels [ 12- 14].
