Sentence examples for multiple pathway members from inspiring English sources

This phenotypic outcome was a result of specific inhibition of the targeted genes and required suppression of multiple pathway members.

Suppression of genes within the RB and p53 pathways illustrates the capacity to use siRNA to dissect functional interactions among multiple pathway members.

Whereas islets treated with control siRNA did not incorporate EDU and those treated for suppression of only RB and p53 siRNA rarely contained cells that incorporated EDU, those that had targeted multiple pathway members often contained clusters of EDU positive nuclei.

Indeed, multiple NF-κB pathway members were all upregulated in CD4+ and CD8+ LPL TEM cells, including NFKB1, NFKB2, REL and RELB, as well as their associated regulatory and target genes, including NFKBIA (IκBα), NFKBID (IκBδ), NFKBIE (IκBε) and NFKBIZ (IκBζ).

Human proteins may have multiple functions and belong to different functional modules, so different signaling pathways may also have some pathway members in common.

Further, many biclustering algorithms allow a gene or a sample to participate in multiple biclusters, reflecting the possibility that a gene product may be a member of multiple pathways.

Although prolactin can transduce signals through multiple pathways, the activation of STAT family members, which are downstream of prolactin and other growth factors has also been implicated in tumourigenesis [ 16, 17].

Certainly, several phase I and II metabolizing enzymes with their family members that take part in multiple pathways play a pivotal role in the detoxification process.

Meanwhile, selenite-induced ROS promoted apoptosis through multiple pathways, such as JNK/ATF2 and Ras homolog gene family, member A/Ser/Thr Rho kinase 1.

Vav3 is a member of the guanine nucleotide exchange factor family, which activates multiple pathways.

We need multiple pathways to achieve the higher standards.