Sentence examples for multiple pathway components from inspiring English sources

Consistent with the effects observed during the blood glucose regulatory dynamics assays, the RIP::IGF-1 transgene seems to inhibit these insulin sensitivity-related effects of the Ghr/bp gene disruption by means of multiple pathway components, namely appendicular skeletal muscular IRS2 and AKT1, and hepatic AKT1.

There are very few studies where multiple eIF4E pathway components have been analysed.

Manipulating multiple MAPK pathway components allows us to examine these combined effects, and several reports have indeed clarified these effects (Table 3).

Thus, the altered levels of multiple Wnt pathway components and Wnt target genes strongly suggest that SV40 ST activates Wnt signaling.

The statistical significance of relationships of y and z with survival show additional prognostic value from examining multiple eIF4E pathway components.

These data constrain the set of possible signaling states for cells expressing multiple Notch pathway components, and support the idea that Notch pathway architecture fundamentally favors heterotypic signaling between cells in distinct signaling states.

Crosstalk occurs when multiple pathways share components.

Multiple agents that target FGFR pathway components are being investigated.

BRCA1 inhibits IGF-I action, so BRCA1 deficiency also leads to increased expression of several IGF-I signaling pathway components in multiple experimental systems, including mice, mammary tumors, and cultured human cells [ 75, 76].

Accordingly, our gene profiling in early Fe deficiency strongly suggests that the induction of genes by Fe deficiency is not begun by a single pathway in the regulation network, but involves multiple pathways and multiple components of activators even in early Fe deficiency.

This collection of miR-203 targets suggests that miR-203 targets multiple pathways, including several components of the Ras signaling pathway, to suppress cell proliferation.