Sentence examples for multiple pathologies underlying from inspiring English sources

31 The limited long-term efficacy of these therapies underscores the significant need for new medications with novel mechanisms of action, as well as the need for combinations of agents targeting the multiple pathologies underlying T2DM.

Rothwell [ 5] identified several situations where a search for clinically important heterogeneity of treatment effects should be considered: first, in case multiple pathologies underlie a clinical syndrome; and second, in diseases with different severity and/or at different stages, or where co-morbidity is frequently present.

The fact that multiple molecular pathologies underlie hyperexcitability-related disorders, such as neuropathic pain and epilepsy, has led to the suggestion that drugs that simultaneously target more than one type of ion channels could treat these disorders more effectively (Goaillard and Dufour, 2014; Klassen et al., 2011; Ratte et al., 2014).

Namely, repeated neuroimaging examination excluded ischemic damage or other cerebral pathologies underlying symptoms.

What is needed is genuine reform that addresses the larger pathologies underlying the rampant corruption plaguing India.

We aimed to study the pathology underlying traumatic temporomandibular joint ankylosis (TMJA).

However, the pathology underlying the marked left ventricular dilatation remains unclear.

Atherosclerosis is the primary pathology underlying heart disease and stroke.

40 By combining multiple q/sq MRI measures, our study confirms work reporting T2 increase in NAWM in early MS 6, 41 and extends these findings by providing new insights into the pathology underlying those changes.

As a first step in preclinical development, we hypothesized that NSCs can influence multiple underlying pathologies associated with AD and improve cognitive deficits.

It is, therefore, not surprising that these two markers may differ in individuals with multiple and different underlying pathologies, such as hypertensive patients with and without type 2 diabetes.