Sentence examples for multiple pathologies such from inspiring English sources

Multiple pathologies such as peripheral neuropathies, skeletal and nervous system disorders and pigment disorders stem from aberrant NC specification, migration or differentiation [9], [10], [11].

However, clinical heterogeneity remains a significant confounder of the case/control study design in AD, due to the likely inclusion of dementia cases with multiple pathologies, such as cerebrovascular disease or other neurodegenerative conditions.

Many of the pathways operating during the intracellular trafficking of bacteria (e.g., autophagosome formation) may have roles in multiple pathologies such as cancer, metabolic diseases, or neurological disorders (reviewed in Rubinsztein et al. 2012) [ 96].

In addition, a small number of patients with multiple pathologies requires such a high number of recurrent hospitalisations and other costly treatments that the cost of their care accounts for the majority of the budgets of health organisations.

Older people with cancer have multiple co-existent pathologies such as cardiac failure and chronic respiratory disease, prolonged recovery phase and rapid deterioration if the illness is left untreated [ 6].

Bmal1 −/− mice demonstrate the development of multiple age-associated pathologies such as cataracts, sarcopenia, reduced hair growth and progressive atrophy of internal organs: the weight of the spleen, muscles and kidneys is significantly reduced in aged Bmal1 −/−mice [ 9].

It is, therefore, not surprising that these two markers may differ in individuals with multiple and different underlying pathologies, such as hypertensive patients with and without type 2 diabetes.

We thereby provide a rational link between the benefit of applying HMGCRIs in brain pathologies, such as multiple sclerosis, Alzheimer's disease and stroke, and the impact on signaling in specific cell types crucial to disease pathogenesis.

Elevated levels of OSM have been detected in several human CNS pathologies, such as multiple sclerosis, HIV-associated dementia, and epileptic seizure [14], [15], [16].

In complex multifactorial pathologies, such as multiple sclerosis, numerous mechanisms may ameliorate disease.

Nontraumatic injuries to the CNS are often caused by degenerative pathologies, such as multiple sclerosis, Alzheimer's disease, and Parkinson's disease.